Following the big storm, Nolan and Tommy find an American astronaut who has been in an induced sleep for the past several decades.

A deadly plague threatens the town; racial tensions rise when the Irathients, who are immune to the virus, are quarantined.

An old war buddy catches up with Nolan at the same time a Castithan criminal with a history of violence enters the picture.

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a…

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava…

A murdered 14-year-old girl leads the detectives to a prominent physician who specialises in reproduction therapy.

An Amateur Night is organized by the new theater troupe, Pinkertons hit town, the students move to their new school, and Hearst makes another move regarding the elections.

The letter is published, Wyatt Earp hits town, delays continue with the theater, and Hearst makes a move.